Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma

To determine whether the PI3K/Akt signaling pathway is involved in the pathogenesis of mantle cell lymphoma (MCL), we investigated the phosphorylation status of Akt and multiple downstream targets in primary MCL cases and cell lines. Akt was phosphorylated in 12 of 12 aggressive blastoid MCL variant...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Rudelius, Martina, Pittaluga, Stefania, Nishizuka, Satoshi, Pham, Trinh H.-T., Fend, Falko, Jaffe, Elaine S., Quintanilla-Martinez, Leticia, Raffeld, Mark
Format: Artigo
Sprog:Inglês
Udgivet: © 2006 by The American Society of Hematology 2006
Fag:
Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895501/
https://ncbi.nlm.nih.gov/pubmed/16645163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-015586
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker