Constitutive activation of Akt contributes to the pathogenesis and survival of mantle cell lymphoma

To determine whether the PI3K/Akt signaling pathway is involved in the pathogenesis of mantle cell lymphoma (MCL), we investigated the phosphorylation status of Akt and multiple downstream targets in primary MCL cases and cell lines. Akt was phosphorylated in 12 of 12 aggressive blastoid MCL variant...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Rudelius, Martina, Pittaluga, Stefania, Nishizuka, Satoshi, Pham, Trinh H.-T., Fend, Falko, Jaffe, Elaine S., Quintanilla-Martinez, Leticia, Raffeld, Mark
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: © 2006 by The American Society of Hematology 2006
Pynciau:
Neoplasia
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895501/
https://ncbi.nlm.nih.gov/pubmed/16645163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-04-015586
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg