Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1

Superantigens (SAGs) bind simultaneously to major histocompatibility complex (MHC) and T-cell receptor (TCR) molecules, resulting in the massive release of inflammatory cytokines that can lead to toxic shock syndrome (TSS) and death. A major causative agent of TSS is toxic shock syndrome toxin-1 (TS...

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Detalhes bibliográficos
Main Authors: Moza, Beenu, Varma, Ashok K, Buonpane, Rebecca A, Zhu, Penny, Herfst, Christine A, Nicholson, Melissa J, Wilbuer, Anne-Kathrin, Seth, Nilufer P, Wucherpfennig, Kai W, McCormick, John K, Kranz, David M, Sundberg, Eric J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852840/
https://ncbi.nlm.nih.gov/pubmed/17268555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601531
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