A novel loop domain in superantigens extends their T cell receptor recognition site

Superantigens (SAGs) interact with host immune receptors to induce a massive release of inflammatory cytokines that can lead to toxic shock syndrome and death. Bacterial SAGs can be classified into five distinct evolutionary groups. Group V SAGs are characterized by the α3-β8 loop, a unique ∼15 amin...

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Autores principales: Günther, Sebastian, Varma, Ashok K., Moza, Beenu, Kasper, Katie, Wyatt, Aaron W., Zhu, Penny, Rahman, A.K.M. Nur-ur, Li, Yili, Mariuzza, Roy A., McCormick, John K., Sundberg, Eric J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949350/
https://ncbi.nlm.nih.gov/pubmed/17560605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.05.038
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