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Full-length p40(phox) structure suggests a basis for regulation mechanism of its membrane binding
The superoxide-producing phagocyte NADPH oxidase is activated during phagocytosis to destroy ingested microbes. The adaptor protein p40(phox) associates via the PB1 domain with the essential oxidase activator p67(phox), and is considered to function by recruiting p67(phox) to phagosomes; in this pro...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1852833/ https://ncbi.nlm.nih.gov/pubmed/17290225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601561 |
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