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Activation of the superoxide-producing phagocyte NADPH oxidase requires co-operation between the tandem SH3 domains of p47(phox) in recognition of a polyproline type II helix and an adjacent α-helix of p22(phox)
Activation of the superoxide-producing phagocyte NADPH oxidase, crucial for host defence, requires an SH3 (Src homology 3)-domain-mediated interaction of the regulatory protein p47(phox) with p22(phox), a subunit of the oxidase catalytic core flavocytochrome b(558). Although previous analysis of a c...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Portland Press Ltd.
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449995/ https://ncbi.nlm.nih.gov/pubmed/16460309 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051899 |
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