Calcium triggers an intramolecular association of the C2 domains in synaptotagmin
Synaptotagmin I is a critical component of the synaptic machinery that senses calcium influx and triggers synaptic vesicle fusion and neurotransmitter release. Fluorescence resonance energy transfer studies conducted on synaptotagmin demonstrate that calcium concentrations required for fusion induce...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18528/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811903/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100127197 |
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