Calcium triggers an intramolecular association of the C2 domains in synaptotagmin

Synaptotagmin I is a critical component of the synaptic machinery that senses calcium influx and triggers synaptic vesicle fusion and neurotransmitter release. Fluorescence resonance energy transfer studies conducted on synaptotagmin demonstrate that calcium concentrations required for fusion induce...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	García, Ricardo A., Forde, Cameron E., Godwin, Hilary Arnold
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 2000
Sujets:	Biological Sciences
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18528/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811903/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100127197
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