Calcium triggers an intramolecular association of the C2 domains in synaptotagmin

Synaptotagmin I is a critical component of the synaptic machinery that senses calcium influx and triggers synaptic vesicle fusion and neurotransmitter release. Fluorescence resonance energy transfer studies conducted on synaptotagmin demonstrate that calcium concentrations required for fusion induce...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	García, Ricardo A., Forde, Cameron E., Godwin, Hilary Arnold
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2000
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18528/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811903/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100127197
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