Calcium triggers an intramolecular association of the C2 domains in synaptotagmin

Synaptotagmin I is a critical component of the synaptic machinery that senses calcium influx and triggers synaptic vesicle fusion and neurotransmitter release. Fluorescence resonance energy transfer studies conducted on synaptotagmin demonstrate that calcium concentrations required for fusion induce...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	García, Ricardo A., Forde, Cameron E., Godwin, Hilary Arnold
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18528/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10811903/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.100127197
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