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Long-range chromosomal interactions regulate the timing of the transition between poised and active gene expression

To understand how mammalian genes are regulated from their natural chromosomal environment, we have analysed the molecular events occurring throughout a 150 kb chromatin segment containing the α globin gene locus as it changes from a poised, silent state in erythroid progenitors, to the fully activa...

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Bibliographic Details
Main Authors: Vernimmen, Douglas, Gobbi, Marco De, Sloane-Stanley, Jacqueline A, Wood, William G, Higgs, Douglas R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852780/
https://ncbi.nlm.nih.gov/pubmed/17380126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601654
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