Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo

Studies have documented the potential antitumor activities of oridonin, a compound extracted from medicinal herbs. However, whether oridonin can be used in the selected setting of hematology/oncology remains obscure. Here, we reported that oridonin induced apoptosis of t(8;21) acute myeloid leukemic...

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Autors principals: Zhou, Guang-Biao, Kang, Hui, Wang, Lan, Gao, Li, Liu, Ping, Xie, Jun, Zhang, Feng-Xiang, Weng, Xiang-Qin, Shen, Zhi-Xiang, Chen, Jue, Gu, Long-Jun, Yan, Ming, Zhang, Dong-Er, Chen, Sai-Juan, Wang, Zhen-Yi, Chen, Zhu
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2007
Matèries:
Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1852250/
https://ncbi.nlm.nih.gov/pubmed/17197433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-06-032250
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