Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Insig renders sorting signal in Scap inaccessible to COPII proteins

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• Sterols regulate cycling of SREBP cleavage-activating protein (SCAP) between endoplasmic reticulum and Golgi
  gan: Nohturfft, Axel, et al.
  Cyhoeddwyd: (1999)
• Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: Oxysterols block transport by binding to Insig
  gan: Radhakrishnan, Arun, et al.
  Cyhoeddwyd: (2007)
• Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols
  gan: Yabe, Daisuke, et al.
  Cyhoeddwyd: (2002)
• Sterol Regulatory Element-binding Protein (SREBP) Cleavage Regulates Golgi-to-Endoplasmic Reticulum Recycling of SREBP Cleavage-activating Protein (SCAP)
  gan: Shao, Wei, et al.
  Cyhoeddwyd: (2014)
• Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins
  gan: Yabe, Daisuke, et al.
  Cyhoeddwyd: (2002)