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Structure-based prediction of C(2)H(2) zinc-finger binding specificity: sensitivity to docking geometry

Predicting the binding specificity of transcription factors is a critical step in the characterization and computational identification and of cis-regulatory elements in genomic sequences. Here we use protein–DNA structures to predict binding specificity and consider the possibility of predicting po...

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Bibliografiske detaljer
Main Authors: Siggers, Trevor W., Honig, Barry
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851644/
https://ncbi.nlm.nih.gov/pubmed/17264128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl1155
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