Mania-like behavior induced by disruption of CLOCK

Circadian rhythms and the genes that make up the molecular clock have long been implicated in bipolar disorder. Genetic evidence in bipolar patients suggests that the central transcriptional activator of molecular rhythms, CLOCK, may be particularly important. However, the exact role of this gene in...

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Bibliografiset tiedot
Päätekijät: Roybal, Kole, Theobold, David, Graham, Ami, DiNieri, Jennifer A., Russo, Scott J., Krishnan, Vaishnav, Chakravarty, Sumana, Peevey, Joseph, Oehrlein, Nathan, Birnbaum, Shari, Vitaterna, Martha H., Orsulak, Paul, Takahashi, Joseph S., Nestler, Eric J., Carlezon, William A., McClung, Colleen A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2007
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851061/
https://ncbi.nlm.nih.gov/pubmed/17379666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609625104
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