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Regulation of dopaminergic transmission and cocaine reward by the Clock gene

Although there are clear interactions between circadian rhythms and drug addiction, mechanisms for such interactions remain unknown. Here we establish a role for the Clock gene in regulating the brain's reward circuit. Mice lacking a functional Clock gene display an increase in cocaine reward a...

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Библиографические подробности
Главные авторы: McClung, Colleen A., Sidiropoulou, Kyriaki, Vitaterna, Martha, Takahashi, Joseph S., White, Francis J., Cooper, Donald C., Nestler, Eric J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2005
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1166621/
https://ncbi.nlm.nih.gov/pubmed/15967985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503584102
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