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Regulation of ryanodine receptor-dependent calcium signaling by polycystin-2
Mutations in polycystin-2 (PC2) cause autosomal dominant polycystic kidney disease. A function for PC2 in the heart has not been described. Here, we show that PC2 coimmunoprecipitates with the cardiac ryanodine receptor (RyR2) from mouse heart. Biochemical assays showed that the N terminus of PC2 bi...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1851053/ https://ncbi.nlm.nih.gov/pubmed/17404231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610324104 |
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