Wordt geladen...
Mad2 overexpression promotes aneuploidy and tumorigenesis in mice
Mad2 is an essential component of the spindle checkpoint that blocks activation of separase and dissolution of sister chromatids until microtubule attachment to kinetochores is complete. We show here that overexpression of Mad2 in transgenic mice leads to a wide variety of neoplasias, appearance of...
Bewaard in:
| Hoofdauteurs: | , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2006
|
| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850996/ https://ncbi.nlm.nih.gov/pubmed/17189715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2006.10.019 |
| Tags: |
Voeg label toe
Geen labels, Wees de eerste die dit record labelt!
|