Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability

The colorectum and uterine endometrium are the two most commonly affected organs in hereditary nonpolyposis colon cancer (HNPCC), but the genetic basis of organ selection is poorly understood. As tumorigenesis in HNPCC is driven by deficient DNA mismatch repair (MMR), we compared its typical consequ...

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Detalhes bibliográficos
Main Authors: Kuismanen, Shannon A., Moisio, Anu-Liisa, Schweizer, Pascal, Truninger, Kaspar, Salovaara, Reijo, Arola, Johanna, Butzow, Ralf, Jiricny, Josef, Nyström-Lahti, Minna, Peltomäki, Päivi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850838/
https://ncbi.nlm.nih.gov/pubmed/12057899
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