Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability

The colorectum and uterine endometrium are the two most commonly affected organs in hereditary nonpolyposis colon cancer (HNPCC), but the genetic basis of organ selection is poorly understood. As tumorigenesis in HNPCC is driven by deficient DNA mismatch repair (MMR), we compared its typical consequ...

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Bibliographische Detailangaben
Hauptverfasser: Kuismanen, Shannon A., Moisio, Anu-Liisa, Schweizer, Pascal, Truninger, Kaspar, Salovaara, Reijo, Arola, Johanna, Butzow, Ralf, Jiricny, Josef, Nyström-Lahti, Minna, Peltomäki, Päivi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2002
Schlagworte:
Short Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850838/
https://ncbi.nlm.nih.gov/pubmed/12057899
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