Proteolysis of AA Amyloid Fibril Proteins by Matrix Metalloproteinases-1, -2, and -3

We recently demonstrated the presence of matrix metalloproteinases (MMPs)-1, -2, and -3 in AA amyloid deposits, which lead us to speculate that MMPs may participate in amyloidogenesis by either processing the precursor protein, or by degrading the amyloid deposits. Here we investigated this theory b...

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Bibliographic Details
Main Authors: Stix, Barbara, Kähne, Thilo, Sletten, Knut, Raynes, John, Roessner, Albert, Röcken, Christoph
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850551/
https://ncbi.nlm.nih.gov/pubmed/11485914
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