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Proteolysis of AA Amyloid Fibril Proteins by Matrix Metalloproteinases-1, -2, and -3

We recently demonstrated the presence of matrix metalloproteinases (MMPs)-1, -2, and -3 in AA amyloid deposits, which lead us to speculate that MMPs may participate in amyloidogenesis by either processing the precursor protein, or by degrading the amyloid deposits. Here we investigated this theory b...

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Autori principali: Stix, Barbara, Kähne, Thilo, Sletten, Knut, Raynes, John, Roessner, Albert, Röcken, Christoph
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850551/
https://ncbi.nlm.nih.gov/pubmed/11485914
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