Transgenic Expression of Cyclin-Dependent Kinase 4 Results in Epidermal Hyperplasia, Hypertrophy, and Severe Dermal Fibrosis

In a previous report we have described the effects of expression of D-type cyclins in epithelial tissues of transgenic mice. To study the involvement of the D-type cyclin partner cyclin-dependent kinase 4 (CDK4) in epithelial growth and differentiation, transgenic mice were generated carrying the CD...

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Autori principali: Miliani de Marval, Paula L., Gimenez-Conti, Irma B., LaCava, Margaret, Martinez, Luis A., Conti, Claudio J., Rodriguez-Puebla, Marcelo L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2001
Soggetti:
Animal Model
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850398/
https://ncbi.nlm.nih.gov/pubmed/11438484
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