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Enhanced Malignant Tumorigenesis in Cdk4-Transgenic Mice

In a previous study, we reported that overexpression of CDK4 in mouse epidermis results in epidermal hyperplasia, hypertrophy and severe dermal fibrosis. In this study, we have investigated the susceptibility to skin tumor formation by forced expression of CDK4. Skin tumors from transgenic mice show...

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Detalhes bibliográficos
Main Authors: Miliani de Marval, Paula L., Macias, Everardo, Conti, Claudio J., Rodriguez-Puebla, Marcelo L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859671/
https://ncbi.nlm.nih.gov/pubmed/14647432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207309
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