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Lack of Cyclin-Dependent Kinase 4 Inhibits c-myc Tumorigenic Activities in Epithelial Tissues

The proto-oncogene c-myc encodes a transcription factor that is implicated in the regulation of cellular proliferation, differentiation, and apoptosis and that has also been found to be deregulated in several forms of human and experimental tumors. We have shown that forced expression of c-myc in ep...

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Detalhes bibliográficos
Main Authors: Miliani de Marval, Paula L., Macias, Everardo, Rounbehler, Robert, Sicinski, Piotr, Kiyokawa, Hiroaki, Johnson, David G., Conti, Claudio J., Rodriguez-Puebla, Marcelo L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC506988/
https://ncbi.nlm.nih.gov/pubmed/15314163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7538-7547.2004
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