Lack of Cyclin-Dependent Kinase 4 Inhibits c-myc Tumorigenic Activities in Epithelial Tissues

The proto-oncogene c-myc encodes a transcription factor that is implicated in the regulation of cellular proliferation, differentiation, and apoptosis and that has also been found to be deregulated in several forms of human and experimental tumors. We have shown that forced expression of c-myc in ep...

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Main Authors: Miliani de Marval, Paula L., Macias, Everardo, Rounbehler, Robert, Sicinski, Piotr, Kiyokawa, Hiroaki, Johnson, David G., Conti, Claudio J., Rodriguez-Puebla, Marcelo L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
Cell Growth and Development
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC506988/
https://ncbi.nlm.nih.gov/pubmed/15314163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7538-7547.2004
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