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Lack of Cyclin-Dependent Kinase 4 Inhibits c-myc Tumorigenic Activities in Epithelial Tissues

The proto-oncogene c-myc encodes a transcription factor that is implicated in the regulation of cellular proliferation, differentiation, and apoptosis and that has also been found to be deregulated in several forms of human and experimental tumors. We have shown that forced expression of c-myc in ep...

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Autori principali: Miliani de Marval, Paula L., Macias, Everardo, Rounbehler, Robert, Sicinski, Piotr, Kiyokawa, Hiroaki, Johnson, David G., Conti, Claudio J., Rodriguez-Puebla, Marcelo L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC506988/
https://ncbi.nlm.nih.gov/pubmed/15314163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.17.7538-7547.2004
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