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Enhanced Malignant Tumorigenesis in Cdk4-Transgenic Mice

In a previous study, we reported that overexpression of CDK4 in mouse epidermis results in epidermal hyperplasia, hypertrophy and severe dermal fibrosis. In this study, we have investigated the susceptibility to skin tumor formation by forced expression of CDK4. Skin tumors from transgenic mice show...

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Hlavní autoři: Miliani de Marval, Paula L., Macias, Everardo, Conti, Claudio J., Rodriguez-Puebla, Marcelo L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859671/
https://ncbi.nlm.nih.gov/pubmed/14647432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1207309
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