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NF-κB Is Activated in Cholestasis and Functions to Reduce Liver Injury

Selected bile acids activate a nuclear factor-kappa B (NF-κB)-dependent survival signaling cascade in cultured hepatocytes. These data suggest that in cholestasis where liver tissue bile acid concentrations are increased, NF-κB should be activated and inhibition of NF-κB should potentiate liver inju...

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Detalhes bibliográficos
Main Authors: Miyoshi, Hideyuki, Rust, Christian, Guicciardi, M. Eugenia, Gores, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850365/
https://ncbi.nlm.nih.gov/pubmed/11238044
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