Cathepsin B Knockout Mice Are Resistant to Tumor Necrosis Factor-α-Mediated Hepatocyte Apoptosis and Liver Injury : Implications for Therapeutic Applications

Tumor necrosis factor-α (TNF-α) contributes to liver injury by inducing hepatocyte apoptosis. Recent evidence suggests that cathepsin B (cat B) contributes to TNF-α-induced apoptosis in vitro. The aim of the present study was to determine whether cat B contributes to TNF-α-induced hepatocyte apoptos...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Guicciardi, Maria Eugenia, Miyoshi, Hideyuki, Bronk, Steven F., Gores, Gregory J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2001
Gaiak:
Regular Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850591/
https://ncbi.nlm.nih.gov/pubmed/11733355
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