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Cathepsin B Knockout Mice Are Resistant to Tumor Necrosis Factor-α-Mediated Hepatocyte Apoptosis and Liver Injury : Implications for Therapeutic Applications
Tumor necrosis factor-α (TNF-α) contributes to liver injury by inducing hepatocyte apoptosis. Recent evidence suggests that cathepsin B (cat B) contributes to TNF-α-induced apoptosis in vitro. The aim of the present study was to determine whether cat B contributes to TNF-α-induced hepatocyte apoptos...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1850591/ https://ncbi.nlm.nih.gov/pubmed/11733355 |
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