Disruption of Integrin Function in the Murine Myocardium Leads to Perinatal Lethality, Fibrosis, and Abnormal Cardiac Performance

The molecular mechanisms that regulate the cardiac hypertrophic response and the progression from compensated hypertrophy to decompensated heart failure have not been thoroughly defined. Alteration in cardiac extracellular matrix is a distinguishing characteristic of these pathological processes. In...

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Bibliographic Details
Main Authors: Keller, Rebecca S., Shai, Shaw-Yung, Babbitt, Christopher J., Pham, Can G., Solaro, R. John, Valencik, Maria L., Loftus, Joseph C., Ross, Robert S.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850360/
https://ncbi.nlm.nih.gov/pubmed/11238056
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