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Disruption of Integrin Function in the Murine Myocardium Leads to Perinatal Lethality, Fibrosis, and Abnormal Cardiac Performance

The molecular mechanisms that regulate the cardiac hypertrophic response and the progression from compensated hypertrophy to decompensated heart failure have not been thoroughly defined. Alteration in cardiac extracellular matrix is a distinguishing characteristic of these pathological processes. In...

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Auteurs principaux: Keller, Rebecca S., Shai, Shaw-Yung, Babbitt, Christopher J., Pham, Can G., Solaro, R. John, Valencik, Maria L., Loftus, Joseph C., Ross, Robert S.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2001
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850360/
https://ncbi.nlm.nih.gov/pubmed/11238056
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