Targeted Disruption of Fibulin-4 Abolishes Elastogenesis and Causes Perinatal Lethality in Mice

Elastic fibers provide tissues with elasticity which is critical to the function of arteries, lungs, skin, and other dynamic organs. Loss of elasticity is a major contributing factor in aging and diseases. However, the mechanism of elastic fiber development and assembly is poorly understood. Here, w...

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Autors principals: McLaughlin, Precious J., Chen, Qiuyun, Horiguchi, Masahito, Starcher, Barry C., Stanton, J. Brett, Broekelmann, Thomas J., Marmorstein, Alan D., McKay, Brian, Mecham, Robert, Nakamura, Tomoyuki, Marmorstein, Lihua Y.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1430262/
https://ncbi.nlm.nih.gov/pubmed/16478991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.26.5.1700-1709.2006
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