Aβ-Induced Inflammatory Processes in Microglia Cells of APP23 Transgenic Mice

A microglial response is part of the inflammatory processes in Alzheimer’s disease (AD). We have used APP23 transgenic mice overexpressing human amyloid precursor protein with the Swedish mutation to characterize this microglia response to amyloid deposits in aged mice. Analyses with MAC-1 and F4/80...

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Hauptverfasser: Bornemann, Klaus D., Wiederhold, Karl-Heinz, Pauli, Chantal, Ermini, Florian, Stalder, Martina, Schnell, Lisa, Sommer, Bernd, Jucker, Mathias, Staufenbiel, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2001
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850262/
https://ncbi.nlm.nih.gov/pubmed/11141480
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