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The Expression and Distribution of the Hypoxia-Inducible Factors HIF-1α and HIF-2α in Normal Human Tissues, Cancers, and Tumor-Associated Macrophages

The cellular response to hypoxia includes the hypoxia-inducible factor-1 (HIF-1)-induced transcription of genes involved in diverse processes such as glycolysis and angiogenesis. Induction of the HIF-regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an im...

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Main Authors: Talks, Katherine L., Turley, Helen, Gatter, Kevin C., Maxwell, Patrick H., Pugh, Christopher W., Ratcliffe, Peter J., Harris, Adrian L.
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2000
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850121/
https://ncbi.nlm.nih.gov/pubmed/10934146
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