Effects of HIF-1α and HIF2α on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts

In cultured clear-cell renal carcinoma (CCRCC) 786-0 cells transfected with HIF1α (HIF-1+), HIF-2α (HIF-2+), or empty vector (EV), no significant differences were observed in the growth rates in vitro, but when grown in vivo as xenografts HIF-2α significantly increased, and HIF-1α significantly decr...

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Autori principali: Biswas, Swethajit, Troy, Helen, Leek, Russell, Chung, Yuen-Li, Li, Ji-liang, Raval, Raju R., Turley, Helen, Gatter, Kevin, Pezzella, Francesco, Griffiths, John R., Stubbs, Marion, Harris, Adrian L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905950/
https://ncbi.nlm.nih.gov/pubmed/20652061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/757908
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