The distribution and expression of the Bloom's syndrome gene product in normal and neoplastic human cells

Bloom's syndrome (BS) is an autosomal recessive disorder associated with a predisposition to cancers of all types. Cells from BS sufferers display extreme genomic instability. The BS gene product, BLM, is a 159 kDa DNA helicase enzyme belonging to the RecQ family. Here, we have analysed the dis...

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Bibliografiska uppgifter
Huvudupphovsmän: Turley, H, Wu, L, Canamero, M, Gatter, K C, Hickson, I D
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2001
Ämnen:
Regular Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2364038/
https://ncbi.nlm.nih.gov/pubmed/11461087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2001.1874
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