The structural determinants of checkpoint activation

Here, we demonstrate that primed, single-stranded DNA (ssDNA) is sufficient for activation of the ATR-dependent checkpoint pathway in Xenopus egg extracts. Using this structure, we define the contribution of the 5′- and 3′-primer ends to Chk1 activation when replication is blocked and ongoing. In ad...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: MacDougall, Christina A., Byun, Tony S., Van, Christopher, Yee, Muh-ching, Cimprich, Karlene A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2007
Konular:
Research Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847708/
https://ncbi.nlm.nih.gov/pubmed/17437996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1522607
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller