Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α

In mammals, maintenance of energy and nutrient homeostasis during food deprivation is accomplished through an increase in mitochondrial fatty acid oxidation in peripheral tissues. An important component that drives this cellular oxidative process is the transcriptional coactivator PGC-1α. Here, we s...

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Detalhes bibliográficos
Main Authors: Gerhart-Hines, Zachary, Rodgers, Joseph T, Bare, Olivia, Lerin, Carles, Kim, Seung-Hee, Mostoslavsky, Raul, Alt, Frederick W, Wu, Zhidan, Puigserver, Pere
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847661/
https://ncbi.nlm.nih.gov/pubmed/17347648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601633
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