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Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1α

In mammals, maintenance of energy and nutrient homeostasis during food deprivation is accomplished through an increase in mitochondrial fatty acid oxidation in peripheral tissues. An important component that drives this cellular oxidative process is the transcriptional coactivator PGC-1α. Here, we s...

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Autori principali: Gerhart-Hines, Zachary, Rodgers, Joseph T, Bare, Olivia, Lerin, Carles, Kim, Seung-Hee, Mostoslavsky, Raul, Alt, Frederick W, Wu, Zhidan, Puigserver, Pere
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847661/
https://ncbi.nlm.nih.gov/pubmed/17347648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601633
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