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Phosphorylation and ubiquitination of the IκB kinase complex by two distinct signaling pathways
The IκB kinase (IKK) complex serves as the master regulator for the activation of NF-κB by various stimuli. It contains two catalytic subunits, IKKα and IKKβ, and a regulatory subunit, IKKγ/NEMO. The activation of IKK complex is dependent on the phosphorylation of IKKα/β at its activation loop and t...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847656/ https://ncbi.nlm.nih.gov/pubmed/17363905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601622 |
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