Interleukin-18 Knockout Mice Display Maladaptive Cardiac Hypertrophy in Response to Pressure Overload

Interleukin (IL)-18 is a cardiotropic proinflammatory cytokine chronically elevated in the serum of patients with cardiac hypertrophy (LVH). The purpose of this study was to examine the role of IL-18 in pressure-overload hypertrophy using wild type (WT) and IL-18 −/− (null) mice. Adult male C57Bl/6...

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Detalhes bibliográficos
Main Authors: Colston, James T., Boylston, William H., Feldman, Marc D., Jenkinson, Chris P., de la Rosa, Sam D., Barton, Amanda, Trevino, Rodolfo J., Freeman, Gregory L., Chandrasekar, Bysani
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847636/
https://ncbi.nlm.nih.gov/pubmed/17250807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.01.030
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