Hematopoietic stem cells and lymphoid progenitors express different Ikaros isoforms, and Ikaros is localized to heterochromatin in immature lymphocytes

The generation of lymphoid cells in mice depends on the function of the Ikaros protein. Ikaros has been characterized as a lymphoid-restricted, zinc-finger transcription factor that is derived from an alternatively spliced message. Ikaros knockout mice have defects in multiple cell lineages, raising...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Klug, Christopher A., Morrison, Sean J., Masek, Marilyn, Hahm, Kyungmin, Smale, Stephen T., Weissman, Irving L.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1998
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9435248/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.2.657
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