تحميل...
Familial Alzheimer disease–linked mutations specifically disrupt Ca(2+) leak function of presenilin 1
Mutations in presenilins are responsible for approximately 40% of all early-onset familial Alzheimer disease (FAD) cases in which a genetic cause has been identified. In addition, a number of mutations in presenilin-1 (PS1) have been suggested to be associated with the occurrence of frontal temporal...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
American Society for Clinical Investigation
2007
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847535/ https://ncbi.nlm.nih.gov/pubmed/17431506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30447 |
| الوسوم: |
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