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Reduced expression of mitochondrial frataxin in mice exacerbates diet-induced obesity
Published evidence suggests that adiposity in humans may be linked to impaired energy expenditure for reasons widely unresolved. We have generated mice with a systemic impairment of oxidative phosphorylation (OXPHOS) due to aP2 cre-mediated targeted disruption, and unexpectedly ubiquitous reduction...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1847459/ https://ncbi.nlm.nih.gov/pubmed/17404227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0611631104 |
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