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An unconventional IAP-binding motif revealed by target-assisted iterative screening (TAIS) of the BIR3-cIAP1 domain

Target-assisted iterative screening (TAIS) has been applied to a random phage-displayed peptide library in a search for novel ligands of the third baculovirus IAP (‘inhibitors of apoptosis’) repeat (BIR) domain of cIAP1. The peptides selected in the screen fall into two distinct specificity groups,...

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Detalhes bibliográficos
Main Authors: Kurakin, Alexei, Bredesen, Dale E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847359/
https://ncbi.nlm.nih.gov/pubmed/17094177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.809
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