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An unconventional IAP-binding motif revealed by target-assisted iterative screening (TAIS) of the BIR3-cIAP1 domain

Target-assisted iterative screening (TAIS) has been applied to a random phage-displayed peptide library in a search for novel ligands of the third baculovirus IAP (‘inhibitors of apoptosis’) repeat (BIR) domain of cIAP1. The peptides selected in the screen fall into two distinct specificity groups,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kurakin, Alexei, Bredesen, Dale E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1847359/
https://ncbi.nlm.nih.gov/pubmed/17094177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmr.809
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