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Intramolecular and Intermolecular Interactions of Protein Kinase B Define Its Activation In Vivo
Protein kinase B (PKB/Akt) is a pivotal regulator of diverse metabolic, phenotypic, and antiapoptotic cellular controls and has been shown to be a key player in cancer progression. Here, using fluorescent reporters, we shown in cells that, contrary to in vitro analyses, 3-phosphoinositide–dependent...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1845162/ https://ncbi.nlm.nih.gov/pubmed/17407381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050095 |
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