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3-D structure and dynamics of protein kinase B—new mechanism for the allosteric regulation of an AGC kinase

New developments regarding the structure and in vivo dynamics of protein kinase B (PKB/Akt) have been recently exposed. Here, we specifically review how the use of multi-disciplinary approaches has resulted in reaching the recent progress made to relate the quaternary structure of PKB to its in vivo...

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Détails bibliographiques
Auteurs principaux: Calleja, Véronique, Laguerre, Michel, Larijani, Banafshé
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682354/
https://ncbi.nlm.nih.gov/pubmed/19568789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-009-0016-8
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