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Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A gene

Epileptic seizures are associated with increases in hippocampal excitability, but the mechanisms that render the hippocampus hyperexcitable chronically (in epilepsy) or acutely (in status epilepticus) are poorly understood. Recent evidence suggests that substance P (SP), a peptide that has been impl...

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Autori principali: Liu, Hantao, Cao, Yuqing, Basbaum, Allan I., Mazarati, Andrey M., Sankar, Raman, Wasterlain, Claude G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC18418/
https://ncbi.nlm.nih.gov/pubmed/10518582
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