Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A gene

Epileptic seizures are associated with increases in hippocampal excitability, but the mechanisms that render the hippocampus hyperexcitable chronically (in epilepsy) or acutely (in status epilepticus) are poorly understood. Recent evidence suggests that substance P (SP), a peptide that has been impl...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Liu, Hantao, Cao, Yuqing, Basbaum, Allan I., Mazarati, Andrey M., Sankar, Raman, Wasterlain, Claude G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18418/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518582/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.12096
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