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Resistance to excitotoxin-induced seizures and neuronal death in mice lacking the preprotachykinin A gene

Epileptic seizures are associated with increases in hippocampal excitability, but the mechanisms that render the hippocampus hyperexcitable chronically (in epilepsy) or acutely (in status epilepticus) are poorly understood. Recent evidence suggests that substance P (SP), a peptide that has been impl...

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Autors principals: Liu, Hantao, Cao, Yuqing, Basbaum, Allan I., Mazarati, Andrey M., Sankar, Raman, Wasterlain, Claude G.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18418/
https://ncbi.nlm.nih.gov/pubmed/10518582
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